HISTORY OF ARTHROSAMID®

Arthrosamid®’s story started two decades ago. The brainchild of the team at Contura, the product had been in human use for various indications since 2000, and a favourable safety profile had already been established.

Arthrosamid® (a registered trademark of Contura A/S.).

HISTORY OF ARTHROSAMID®
Clinical Innovation

Arthrosamid®: A defining breakthrough in OA treatment.

Developed over two decades, this non-biodegradable hydrogel offers a durable, minimally invasive alternative to cushion the joint and relieve pain.

Safe & Established

Built on 20+ years of hydrogel research with a favorable safety profile.

CE Marked

Approved in Europe (2021) for symptomatic treatment of knee osteoarthritis.

Delays Surgery

Joint-preserving injection intended to provide long-acting pain relief.

Arthrosamid Packaging
Treatment Overview

What is Arthrosamid®?

A breakthrough single-injection treatment designed specifically for patients suffering from knee osteoarthritis.

  • Single Intra-articular Injection

    Administered directly into the knee cavity to cushion the joint, providing sustained relief from pain and stiffness.

  • Non-biodegradable Hydrogel

    Composed of 2.5% cross-linked polyacrylamide and 97.5% water. It integrates with the tissue rather than degrading over time.

  • Alternative to Existing Therapies

    A viable option for patients where conventional therapies (like standard HA injections) have failed to provide lasting relief.

Mechanism of Action

How does Arthrosamid® work?

Restoring cushioning and lubrication directly inside the knee joint capsule.

Step 01

Precise Injection

Arthrosamid® is injected into the inner joint cavity (synovial space) under image guidance.

Step 02

Integration

The hydrogel combines with synovial fluid and integrates into the lining of the joint capsule.

Step 03

Cushioning

Forms a durable, cushion-like layer that reduces stiffness and improves overall mobility.

Clinical Note: The procedure is performed by a qualified clinician. Ultrasound or X-ray guidance is used to ensure the hydrogel is delivered accurately into the joint space for maximum effectiveness.

3D illustration of knee joint injection mechanism
Patient Outcomes

What are the benefits?

Long-acting pain relief and improved mobility from a single injection.

Reduced pain & stiffness

Reduced pain, less stiffness and easier movement as the joint is cushioned.

Long-acting relief

Long-acting relief from a non-degradable hydrogel that is designed to stay in the joint.

Potential to delay surgery

For some people, Arthrosamid® may help postpone or potentially avoid knee surgery.

Clinical Trial Insights

Week 4

Patients reported a meaningful reduction in pain from around week 4 after the injection.

1 Year

Improvements were maintained at 1-year follow-up in the study population.

*Individual results vary. Your clinician will advise whether Arthrosamid® is appropriate for you.

Treatment

1 injection

A single intra-articular injection, performed by a trained clinician.

Onset of effect

Week 4

Pain reduction from around week 4.

Durability

1 Year

Relief maintained at 1 year.

Technology

Non-degradable hydrogel

The gel is designed not to break down, supporting long-acting cushioning of the knee joint.

Safety & Tolerability

Is Arthrosamid® safe?

A hydrogel with over 20 years of clinical use history.

20+ years of clinical use

The hydrogel technology has been used in humans since 2000 for different indications, with a favourable safety profile.

No serious side effects

In clinical trials, no serious side effects were reported that were linked to the hydrogel itself.

Mild, temporary reactions

Common side effects were mild to moderate pain or swelling around the injection site, generally short-lived.

Safety Profile Summary

Overall, the hydrogel’s safety profile has been confirmed across multiple uses in the body. Your clinician will review your medical history and explain potential risks and benefits before treatment.

*As with any medical procedure, individual experiences vary. Always follow the advice of your healthcare professional and report any unexpected symptoms after your injection.

Doctor explaining knee anatomical model to patient
Recovery & Activity

When can I get back to normal activity?

A short recovery period with guidance from your clinician.

Do

As advised by your professional

  • Resume light everyday activities when your clinician says it is safe to do so.

  • Take short, gentle walks around your home or workplace as tolerated.

  • Listen to your knee, rest when needed and follow any aftercare advice from your clinic team.

Avoid

First few days (follow advice)

  • Strenuous weight-bearing exercise such as running, tennis or high-impact classes.

  • Long walks, hikes or standing for prolonged periods soon after the injection.

  • Heavy lifting, deep squats or sudden twisting movements until your clinic team advises they are safe.

Note: Everyone recovers differently. Your healthcare professional will give you personalised guidance on when and how to increase your activity after Arthrosamid®.

Silhouette of a trail runner at sunrise
Active Lifestyle
Next Steps

Start your journey to pain-free movement.

Booking your consultation is simple. We start with a friendly, no-obligation chat to understand your needs.

1

Book a Discovery Call

A complimentary 15-minute call with our team to discuss your symptoms and suitability.

2

Clinical Assessment

Visit our clinic for a comprehensive review, including imaging if required.

3

Treatment

Receive your Arthrosamid® injection and begin your recovery with our support.

Ready to find out more?

Speak directly with our specialists to see if this treatment is right for you.

Book a Free Discovery Call

No referral needed • No obligation