The Best Alternative to Knee Replacement for Elderly Patients: Arthrosamid® Injections

Many older adults go on to develop osteoarthritis – a degenerative “wear-and-tear” condition that commonly affects the knees. As the joint surfaces gradually break down, everyday movements such as walking, climbing stairs or standing up can become painful and stiff.

In more advanced cases, orthopaedic specialists often recommend knee replacement surgery. However, for elderly patients this kind of major operation is not always ideal. Age-related health issues, a longer recovery period, and the risk of complications can make surgery feel daunting or unsuitable.

The good news is that there are non-surgical alternatives to knee replacement for elderly patients. One of the most promising options is Arthrosamid®, an injectable hydrogel treatment designed to reduce pain and improve knee function by lubricating and cushioning the joint.

What Is Arthrosamid®?

Arthrosamid® is a polyacrylamide hydrogel injection used to treat knee osteoarthritis. It is injected into the intra-articular space – the space inside the knee joint between the cartilage surfaces of the femur (thigh bone) and tibia (shin bone).

The gel is made from approximately 95% non-pyrogenic water and 2.5% cross-linked polyacrylamide. Once injected, Arthrosamid® integrates with the tissues lining the joint (the synovial membrane). The synovial membrane is responsible for producing synovial fluid – the natural “oil” of the knee that keeps the joint moving smoothly.

Over the weeks following treatment, many patients notice:

• Reduced knee pain
• Less stiffness
• Improved mobility and function

Clinical data suggest that within around 27 weeks of an Arthrosamid® knee injection, patients may experience meaningful improvements in pain and movement.

How Does Arthrosamid® Work in Elderly Patients?

In knee osteoarthritis, the synovial fluid can become thinner and less effective, and the joint surfaces may be roughened. This leads to increased friction between the bones, causing pain, swelling and stiffness.

Arthrosamid® works by:

• Acting as a long-lasting cushion and lubricant inside the knee joint
• Supporting the function of synovial fluid, reducing friction between the cartilage surfaces
• Absorbing shock when you walk, stand or climb stairs

By improving the lubrication and cushioning of the joint, Arthrosamid® can help relieve pain and make movement more comfortable. This is why it is increasingly considered one of the leading alternatives to knee replacement for elderly patients who are not ready for, or suitable for, surgery.

Why Arthrosamid® Is a Revolutionary Alternative to Knee Replacement for Elderly Patients

There are several reasons why Arthrosamid® injections are seen as a valuable alternative to knee replacement in older adults.

1. Non-invasive treatment

Arthrosamid® is a non-surgical treatment. The gel is injected into the knee joint using a needle, usually under local anaesthetic.

Because it is non-invasive:

• There is no large incision
• Risks associated with major surgery, such as wound problems, internal fractures or anaesthetic complications, are avoided
• Elderly patients, who may have other medical conditions, often find this a more manageable option than a full joint replacement

This makes Arthrosamid® an attractive alternative to knee replacement for elderly patients who wish to avoid or delay surgery.

2. Shorter recovery time

Unlike knee replacement, which can take weeks to months of rehabilitation, recovery after Arthrosamid® is usually much quicker.

In most cases:

• Patients can go home the same day
• Normal daily activities can often be resumed within hours to a few days, depending on individual comfort and medical advice

This quicker, more straightforward recovery is a key reason many patients and clinicians consider Arthrosamid® one of the most practical alternatives to knee replacement for elderly people.

3. Safe and effective solution

Arthrosamid® is made from a non-biodegradable polyacrylamide hydrogel, designed to remain in the joint and provide long-term cushioning. Clinical studies have shown that it can be a safe and effective treatment for knee osteoarthritis symptoms.

A few important points:

• The material has been carefully studied in orthopaedic use
• It is not known to break down into harmful by-products
• In some cases, the injection can be repeated if needed – for example, every six to twelve months – depending on the patient’s symptoms and their specialist’s advice

In contrast, knee replacement is a major operation that carries surgical risks and may eventually require revision surgery if the artificial joint wears out.

4. Fewer side effects compared with surgery

All medical treatments carry some risk, but Arthrosamid® injections generally have milder side effects than knee replacement surgery.

After an Arthrosamid® injection, some patients may experience:

• Mild temporary pain at the injection site
• Local swelling or warmth in the knee

These effects usually settle within a short period.

By comparison, knee replacement surgery can be associated with more serious complications such as:

• Blood clots
• Infection
• Implant failure or loosening
• Damage to surrounding tissues

For elderly patients, reducing the risk of serious complications can be a major advantage of choosing a non-surgical alternative.

How Long Does the Effect of Arthrosamid® Last?

The duration of benefit from Arthrosamid® can vary depending on:

• The severity of osteoarthritis
• The patient’s overall health and activity level
• Individual response to the treatment

However, clinical studies have reported that many patients experience:

• Noticeable pain relief within around 6 months of the injection
• Continued improvement or maintenance of benefits for up to 12 months or longer

In a 2021 study, a large proportion of patients treated with Arthrosamid® were able to manage pain and stiffness for at least a year after a single injection, with improved knee mobility and function during that period.

Longer-term research is ongoing to understand how durable the effects are over several years, and whether repeat injections can safely maintain or extend the benefits.

Are Arthrosamid® Injections Safe and Reliable? What Do the Experts Say?

Arthrosamid® has been carefully researched and is supported by clinical data for the treatment of knee osteoarthritis.

Key points from the evidence so far include:

• Studies have shown significant reductions in pain and improvements in function in many patients
• The safety profile appears favourable, with mostly mild and temporary side effects
• Arthrosamid® has received regulatory approval (including a CE mark in Europe) for use as a symptomatic treatment for knee osteoarthritis

Overall, the available evidence supports Arthrosamid® as a safe, reliable and effective alternative to knee replacement for elderly patients, particularly for those looking to avoid or postpone major surgery.

For an even better outcome, many experts recommend combining Arthrosamid® injections with physiotherapy for arthritis. Targeted exercises can help:

• Strengthen the muscles around the knee
• Improve balance and joint stability
• Support mobility and independence in daily life

Is Arthrosamid® Right for You?

While Arthrosamid® is a promising option, it is not suitable for everyone. Factors such as overall health, severity of osteoarthritis, current medications and personal goals all need to be considered.

If you are an older adult struggling with knee pain and wondering about alternatives to knee replacement, it is important to:

• Discuss your symptoms with your GP or orthopaedic specialist
• Ask whether Arthrosamid® or other non-surgical treatments may be appropriate
• Consider a combined plan including injections, physiotherapy, weight management and lifestyle changes

Arthrosamid® injections offer a modern, non-surgical approach that can help many elderly patients reduce pain, move more comfortably and delay – or in some cases avoid – knee replacement surgery.