Rethinking Knee Osteoarthritis: How Joint Mechanics and Inflammation Shape the Disease
Discover the latest insights into knee osteoarthritis, a chronic joint condition influenced by both mechanical stress and chronic inflammation. This article explores how biomechanics—such as knee alignment and joint loading—interact with inflammatory responses to drive knee osteoarthritis progression, going beyond the outdated “wear and tear” perspective. Learn how cartilage damage, bone changes, and inflammatory molecules like cytokines create a cycle of pain and deterioration in the knee. Find out how advances in understanding these dual mechanisms are shaping new, more effective treatment strategies, including personalized therapies that target both joint function and inflammation, offering hope for better management and improved quality of life.
