Methotrexate in Knee Osteoarthritis: Balancing Hope with Practical Challenges
Methotrexate, a medication traditionally used for rheumatoid arthritis, is being explored as a treatment for knee osteoarthritis due to its inflammation-reducing properties. This article explains how methotrexate works, summarizes research on its effectiveness and safety for knee osteoarthritis, and discusses dosing challenges and side effects such as nausea and liver changes. Early studies suggest the drug may relieve symptoms and protect joint cartilage, but personalized dosing and regular monitoring are crucial to manage risks. Ongoing research and clinical trials are needed to clarify methotrexate’s long-term role in osteoarthritis care, highlighting the importance of balancing innovation with patient safety.
